I was on Seroquel for 7 years. It didn't help me in any way except sleep. I gained 147lbs on it over the years (I started at 110lbs). Psychiatrists kept insisting that I needed to stay on the stuff. I now have high blood pressure, high bad cholesterol, and I'm on the line between prediabetes and diabetes (I'm on meds for the health issues now).
At the end of the summer I was finally able to go off the Seroquel. The medication for diabetes definitely curbs my appetite, which was crazy on Seroquel. But since going off Seroquel, even with the med for diabetes, I have gained 7lbs. For some people Seroquel is a magic pill. For me it was poison. I am so angry because I never told a pdoc NO, I will not continue taking Seroquel.