I did 7 years of brutal residency and fellowship after medical school to get my supposedly dream job. Guess what? I didn't really enjoy it. I do think I was pretty good at patient care. But what I really was passionate about was building companies. I realized I should have gone to business school. But it was too late.

Fortunately, I got to build a couple of nice little companies before I got sick, but that was just dumb luck.

You need to find what your passion is and then go do that. If that means you have to move to a big city, then move. If that means you re-train in animal care or astronomy or the grocery business--go do that.

Life is short. Don't waste it doing something you'r not into, even if at one time, you thought you were. You gotta do what you enjoy.