rose1985, have you ever used low dose Seroquel? I take a somewhat large dose of Seroquel XR and my anxiety levels have been pretty low, comparitively, for years. But when I do get some anxiety, I have used low dose of the regular instant release Seroquel as a prn medication. It has helped me. Even doses of only 25 to 50 mg. Doses that low, especially 25 mg, don't even make me tired anymore. I got used to it.