Good Morning, Scooter,

I know you have felt Mirapex has been helping.
With symptoms increasing it becomes a matter of weighing pros and cons. Yet, weighing the pros and cons of what, exactly.

As I understand things, Wellbutrin and Mirapex are both dopamine agonists. With both dopamine agonists on board, I might ask if it makes sense to drop Wellbutrin and stay on Mirapex awhile in order to see what happens? Maybe I have no clue,which is also quite possible! Intuitively, it makes sense to me to cut the least helpful dopamine agonist first and go with the Mirapex for awhile, since you have found it helpful, working with it to see what transpires.

This is merely a question/proposal I might pose if I was not quite ready to discontinue Mirapex.

I think we both have found Mirapex somewhat helpful, which has helped us to be a bit more hopeful that it can be a very helpful med.
I guess then the question becomes: Is it helpful enough? With a history of "treatment resistant" depression, which now does respond to a med, even with a partial response, it could be tough to give up that med? I'd find it very tough to give it up; yet, I don't want to project my own feelings onto you or onto your experience with Mirapex.

If you find you'd prefer to stay with the Mirapex longer, I'd propose this to my pdoc for discussion.
I know my pdoc and I barter with one another fairly often, even concerning Mirapex dosages.

If you are ready to move on and try something different, this is cool, too.

I just felt I should respond to your post, as I think Mirapex has been a med which has given you a bit of relief and possibly some hope?

Either way, I absolutely hope the treatment course you take will be most helpful for you!
As always, my very best to you and to yours!