I have two types of replies - the goofy lighten-the-mood kind and the direct in-your-face kind. Goofy - to get people to lighten up a bit and think about the absurdity of who we are. Direct - I avoid saying things like "it will be OK" or "tomorrow will be better". In truth, we all need to change course from our demons or they'll keep following us. So I say what needs to be said. I avoid posting to anyone who seems to be in crisis because neither strategy helps. I'm someone who puts his fist through the wall (see: Andy Bernard) but that's the extent of my experience with BP.