I was on 75mg for a long time. At first it seemed to help, but I think I got used to that dose and it wasn't really helping me like it was supposed to. The begining of February I was increased to 150mg. The psychiatrist told me that 75 mg was a "baby" dose. I did notice a big difference with the increase. I am now at 225mg. I have not noticed as much of a difference from 150 to 225 as I did from 75 to 150. I don't know if it helps for OCD because I don't have that. I hope this helps a little.