I have been on anywhere from 750 to 1750. Those doses were by different Pdocs, I have no idea why the first made me take 1750 and the next dropped it by 1000. My levels were apparently fine at 750. I dont feel like it has been a useful drug for me because of the amount of breakthrough symptoms however the Pdoc seems to think it is helpful, not sure what they are going off of. Cant complain about side effects though, I had absolutely none in the years I was on it.