My youngest nephew had both a bipolar NOS diagnosis (he mostly had depression) and Asperger's. I'm not quite sure how having both affected him. I'm sure it didn't help. My older nephew has Asperger's and has had depression. Both exhibited symptoms obsessive compulsive symptoms, too. My eldest nephew is likely a hoarder, or that's what my sister believes. Both seem(ed) unable to really live on their own. I believe their symptoms (in the Asperger's range) were/are pretty severe. My family lost my youngest nephew in 2017.