
Feb 18, 2020, 08:32 PM
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Member Since: Jun 2016
Location: U.S.
Posts: 2,586
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Quote:
Originally Posted by still_crazy
hi. i take abilify, now at 20mgs. zyprexa was OK till I hit 5mgs or so...akathisia, despite ongoing Klonopin treatment already in place. -eek- Abilify has a higher % of akathisia, in big studies, but its never caused problems for me.
some people take metformin by Rx with zyprexa. given that it can cause metabolic complications even without massive weight gain (this, according to one of many former shrinks, lol), I'd say that might be something worth looking into. for whatever reasons, many psychiatrists will have a family or general practitioner do the metformin, if its a viable option for you.
on the plus side, in the big studies on people with Schizophrenia, Zyprexa -did- outperform the other atypicals and perphenazine on some key measures of mood improvement, positive and negative symptoms, etc. on the downside...weight, metabolic stuff, plus everything that comes with every tranquilizer, ever (EPS, TD, akathisia, dysphoria, etc.) remains a possibility with zyprexa, too.
has your doctor talked about Vryalar or Rexulti? They're the "new Abilify-ies," basically...D2 partial agonists. The only "deal" there is that the D2 partial agonism sometimes=less toxic drug, overall, than most other antipsychotics. just a thought.
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I did not know that about metformin being used, That;s interesting. For some reason my pdoc said she won't do Rexulti. She doesn't think it will do enough for me, so I guess that's out. I never tried Vrylar. I wonder how she would feel about that.
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