As others participating here, I suffer from longterm depression and anxiety. Circumstances have permitted me time to consider my conditions, perhaps too much time.

The human organism is a "system of systems," a marvelous complex of negative and positive feedback loops that folds in both the physiological and psychological. Many of those loops are endocrine-hormonal.

Logic can lead astray, but I wonder to what extent the study of depression and anxiety might benefit from the inclusion of endocrinology, and necessarily metabolic homeostasis, in the science?

Some of us certainly are, and the cost-effective techniques beloved of medical bureaucracies tend to gag on us.