[QUOTE=Rohag;6780666]

The human organism is a "system of systems," a marvelous complex of negative and positive feedback loops that folds in both the physiological and psychological. Many of those loops are endocrine-hormonal.

Logic can lead astray, but I wonder to what extent the study of depression and anxiety might benefit from the inclusion of endocrinology, and necessarily metabolic homeostasis, in the science?

It makes sense, Rohag. For example, I'm postmenopausal now, but when I did have a menstrual cycle I could practically set my clock by the mood changes I'd endure depending on where I was in the cycle. When my hormonal level would drop right before the onset of a period I would be suicidally depressed, hardly able to get out of bed in the morning. I believe that coincides with a measurable drop in hormonal level.

At the onset, when all the hormones came rushing back, I felt FANTASTIC.

I believe this is a known medical phenomenon.