I tried both latuda and saphris. With Saphris I needed to wander around a lot and latuda I don't remember what went on there, except that I have issues with a LOT of meds. I did try Zyprexa for over a year and all it did was make me gain weight and kill my metabolism and raise my triglycerides and give me pre-diabetes. I think you've made a good decision to stay away from that. How many meds have you tried? I've tried a lot, but thankfully I can tolerate Haldol. Seroquel works for me, but its got the weight gain aspect to it, too, though not nearly as bad as Depakote and Zyprexa I don't think.