Lamictal has always been activating for me. I must take it along with a good amount of antimanics. I've only needed 100 mg for the last eight years. There was a point about 13 years ago that I took as much as 300 mg Lamictal, along with Abilify, but it made me severely manic with psychosis and I struggled to get out of that mania, despite hospitalizations following that. Abilify was not a sufficient antimanic for me.

As written, I only take 100 mg Lamictal, and I take it in the morning. I'm not sure what would happen if I took it at night. I take plenty of sedating medications at night. My morning cocktail, including Lamictal, is not sedating at all. In fact, my psychiatrist had to recently add 100 mg Seroquel XR in the morning, beyond my evening 600 mg Seroquel XR. And currently, I am still kicking butt during the day.