Everyone reacts differently to meds. Abilify for me was a freaking Monster, Akathesia from hell.. Seroquil XR was a god send for awhile.
Meds are often like coping skills.. You keep throwing one at it until you find one that sticks and helps you find stability.
I hope it helps you.. Yes often when people take something, start to feel good and think they no longer need the med, they quit.. life goes to hell and hop back on the med and it can lose its effectivness, Honestly I have never met a Bipolar person that hasn't dumped there meds a couple times LOL It is just part of Bipolar. But over time most people learn that its not a good idea..