I have been having a mixed episode for the last 2 days. My psychiatrist says my medicine is not yet to a therapeutic dose (changing as well). She's upping me slowly to watch for side effects. Anyhow, these things totally suck. Yesterday I plummeted from an obsessive high to a terrible depression. I put myself out with benadryl because I couldn't stand the crying anymore. Today when I felt the depression coming on, I convinced myself to sleep. Just got up and I feel a fair bit better. With the mixed episodes though, I experience worse depressions than I ever have in my life.