The opioids are a concern. Her being verbally abusive is also very concerning. Her sudden desire to buy new underwear, have more sex and lose weight could all be signs of cheating, along with being on the phone all night, but it's hard to know without real proof. I would be concerned, if I were you, and there are legitimate suspicious things going on. At the very least, you have caught her using opioids, and that's a problem, along with the verbal abuse. Is that the first time she's been abusive towards you?