What was it? Like many of us, I have been on a bunch. Probably the worst for me, though, overall, has been Naltrexone--an opiate antagonist I had to take a million years ago. Had the worst psychosis of my entire life--and that is saying something. Just hideous. I know it is a life saver, but not good for me.

I would also say that Seroquel has been pretty close to the worst for me at times. Gave me some kind of crazy, wacky, buzz-high thing for awhile. Weird.