Well BP, I tapered off of prozac, which had always worked well for me, to try the more “natural” St. John’s Wort. Once it built up a certain level in my blood I began to feel very hyper-emotional and couldn’t control my crying, weepiness, and just general upset. Once I dc’d it I returned to my usual dysthymia low level of functioning.
FYI I am simply depressed/anxious, not bipolar.