I have taken it only briefly, but it caused some serious side effects for me. I know for many it is a lifesaver though. It is, to my knowledge, the first atypical antipsychotic. Meaning it is different, chemically speaking, than the older, first generation antipsychotics (to my layperson brain). Some doctors once suggested that I take it again to help with my impulsivity, but I think that lifestyle changes will help with that more, perhaps. But if you're considering taking clozapine, it might be wise to get a full medical exam before. Just to confirm that clozapine won't exacerbate any other medical things. I don't know, that is just what the doctors suggested I do before I took clozapine. Wishing you well.