So my understanding is that fish oil stimulates bdnf....colloquially known as brain fertilizer lol....it’s also part of the make up of the brain.....it only works if you’ve got Brain [emoji3447] damage though so ymmv.

The epa is more for heart and dha is more for your brain.

As far as supplements not working...I know the fish oil works for me, I couldn’t remember where I parked my car or other things like an assignment from two days ago or even two hours until I started taking it. My focus improved dramatically....I could read novels again. It was the only thing I changed. N=1

Also I know my mom took the AERDS vitamins for her eyes due to macular....studies show it helps.

Sarcosine also has been used in trials. The main difference is reliability like is the active ingredient consistent in the supplement and has it been around for 1000s of years so they can’t really patent it. I’ve seen a prescription fish oil now btw.