Good for your for standing up for yourself, Ruby. No matter what you said, the next day is a new day and your supervisor/co-worker needs to treat you and themselves and each other with respect. There is no place for holding grudges in the workplace (or anywhere else, for that matter).

Karen had no business telling that to the other co-worker either. If Karen is your supervisor she should be fostering good relationships among herself and employees, not encouraging or continuing any strife that may or may not have been present.

Yes, it would have been better if you had not said that about the GM because it appears that it inadvertently offended this woman--but now at this point she needs to get over it.

If you have a disability and the company knows about it, no one is supposed to be abusing you because of it.

You'll want to be careful about using popular terms like "karen" at work. Even if it is very popular, it is better to just call people by the name they want you to use, and to not refer to them by popular terms like karen on the job. Some people find that very upsetting. I made the mistake of asking a young man (this was years ago) what the popular term was for his generation--Gen X, Gen Y, slacker, what was it..? And he became almost hysterical screaming he was not a slacker. I wasn't trying to call him a slacker; to this day I still don't know the answer to my question--but I learned not to ask it.