Hi BethRags. I have taken my 100 mg Lamictal in the morning the whole 8 years. It doesn't make me tired at all. In fact, I had to start taking 50 mg of my 700 mg Seroquel XR in the morning because I was ramping up way too much during the daytime. I still am to a small degree. Tegretol XR doesn't make me tired, either. I think a lot of medications that help sedate in the evening, don't so much when taken in the morning. I guess it depends on the medication and/or the person.