I've had 2 colonoscopies & didn't have any problems with either one. (The surgeon did remove one polyp during the second procedure.) I'm well overdue for a third. (I have a family history as well.) But I've pretty-much decided not to do it again. I have to die of something. And I'm not a person who wants to live to be 80 or 90 years old to say nothing of 100!
I'm already too old.
I am under the impression that problems tend to occur more with older people than they do with younger folks. I don't know if it's still the case, but my understanding has been that they don't typically do routine colonoscopies on people over the age of 70 due to the potential for damage. But perhaps that has changed as the way the procedure is done has improved over time. I don't know. I have no experience with home colon cancer screening tests.