Hi MarcusAurelius. I understand your concern about potential medication dose/change adjustments, but at the same time I would want some effort to be made to help you get out of your depression. Perhaps you can express this concern/dread with your doctor and he could think of something (or some medication) that may be "softer and friendlier" to adjust to. Or, there's always therapeutic tools that we can continue to use. Maybe a new therapeutic or lifestyle tool is in order.