I'm sorry to hear that your sister doesn't want a relationship with you anymore. Were you two ever close to each other? Did anything happen to make her pull away from you? As for not expressing interest in men, maybe she prefers to keep her feelings private? Or maybe she might be asexual? Is she a private person? It sounds like she might be a private person. I didn't share to many personal feelings with my younger sister or my family since they'd usually end up judging me or end up making fun of me. They didn't respect my privacy at all. My dad laughed when he read my diary and he'd try to tape record our phone conversations. My mom would try to spy on us a lot, ugh.

Did you and your family ever make her feel judged or stupid? Did you ever reveal a secret of hers? Don't feel to bad. I was never close to my younger sister. Things became worse as when we became adults. We're not both in our 40's and we haven't spoken to each other in over 4 years since our last fall out. She just snapped at me for a very stupid reason. Long story short, I don't trust her since she has been involved in a lot of shady stuff in the past including identity theft. Her b.f was at fault she said and it was all his idea and she didn't know what he was up to, but she suspected something. She was questioned but not arrested.

He got deported since he was an illegal alien. She has always been a jealous, fake, competitive and stuck up brat. She is ashamed of me since I have depression and anxiety. She has never really been that nice or supportive of me. She made fun of me growing up and be mean to me but nice to her friends.

Do your parents favor either or you? If so, then that could be part of the problem. My parents favor my sister since she kisses their butt. I don't. Maybe things will change in the future between you and your sister. You're both still young. Did you try talking to her and telling her how you feel? Maybe write her a note and slide it under her door. If she chooses to still ignore you, then it's her loss.