I hope the 'Karen' phenomenon burns out quickly. Butter Toast and Apollite made some excellent points, and wrote them much better than I could have done.
On one hand, it strikes me as sexist. It's an attack on women speaking up for themselves when they feel wronged. But on the other hand, some people really do go too far in their protests, and behave badly, and lose their credibility in doing so, and they do make laughing stocks out of themselves. They have no one to blame but themselves for being turned into memes.
Mixed feelings. I think it boils down to how you conduct yourself when you feel a wrong has been done.