In my case, despite any possible (or likely) effects on me metabolically, Seroquel XR is a great medication. My moods have been better than they have for well over a decade. Unlike many antipsychotics, Seroquel XR has not given me hyperprolactinemia, akathisia or any other form of EPS, and serves as a great sleep aid. Also, over the years, Seroquel XR (especially the XR) has been closer to weight neutral than other antipsychotics, like Zyprexa or Risperdal or Invega. It certainly is the case that some people have slightly to vastly different reactions to Seroquel XR than me, but I do think many agree that it is friendlier especially in terms of EPS and hyperprolactinemia. I also know that many really do appreciate it as a sleep aid.

Seroquel XR seems equally helpful at curbing and preventing both depression and mania for me. I can't say that about certain other antipsychotics. I also find that Seroquel (regular and XR) are helpful at curbing and preventing anxiety, for me. Honestly, so far I find it to be the least of the antipsychotic evils, in my experience. Unfortunately, I do seem to need an antipsychotic along with my moodstabilizers (anticonvulsants). Whether or not that changes in the future is TBD.

I know Lithium is some people's miracle drug. For me, it was downright nasty. We're all different!