Totally agree with you, Break.
My reply was very partial, I think it’s because it’s a long time since I felt what I think you are feeling.
After reading your post, I quickly remember when I was working away from home and stayed there by myself, in the town where my work was and I felt less lost and a little better during the labor days. Since I had a little of interaction those days. Weekends and day-off were as a prison. At least, this is how I felt it. Pretty frustrated.

I’m curious as to why some extroverts are coping so well with the situation. I’m trying to put myself on their shoes and for me, telephone or any other means of online communication counts for me as an interactions. I guess they have a large net of contacts and they can connect with them using telephone, video-chat, you can even do it among a group of people. I couldn’t do it so much. So. Maybe these extroverts, for whatever reason, they live their lives mainly around online connections. And they don’t see a difference. I don’t know. You could ask them.