AHH .There the trick. How to stay manic but limit how high and not to get depression .First off learn about you meds. Seroquel a great drug if you know how and why you are taken it . Seroquel works for 24 hours and controls your manic side . So the trick is to take it at night at the same time every night and 8 to 10 hours before you would wake up .So I take it at 8:30 and get up at 7:00 any time later I'm dead tried all day .Do not take it during the day!!! You will just sleep all the time and worst you will never feel manic.

Now you have to find the right dose for you .The amount that clams you down but leaves you a little bit manic . Mines 200 mg. and I have a extra dose as back up in case my manic starts to spin out of control .Seroquel XR will release alttle all day so you will be sleepy all day and wont be able so sleep of the side effect .

As far as weight gain well thats rough but alot of meds. put on weight . Fat and happy or skinny and sad .But like anything you can find a happy middle .