I haven't had an Anti-depressant in 10 years. I was on them 11 years ago and we found them to make me manic. Unfortunately I still get depressed but mostly its mild depression. Until last year that was a severe depression I was suicidal. I hadn't been like that in 8 years. I just had to ride it out myself (which isn't easy) I also got extra support from my Psychiatrist and CPN (Community Psychiatric Nurse) and Therapist. They refuse to give me Anti-depressants just incase I go manic its hard as riding it out is really difficult