I take seroquel only. It does not solve my depression, but it is less impactful than without seroquel.

In the past anti-depressants have caused a ****-show of rapid cyling and hypomania, but I'm thinking of asking for one again after many years without. My depression while not as devestating as before seroquel it is chronic companion that I have to live with. I'm questioning if there could be relief from it instead of just living with it, and coping my best.

I'm not sure if that's helpful at all, but that's my experience.