Yeah, I get that too. It wakes me up in the middle of the night, and I also get it in the mornings sometimes and throughout the day. I think it's associated with the depression but like others I've also noticed that it tends to be the worst during dysphoric mania. My depression tends to drift from "just" depression towards agitated depression or dysphoric mania from time to time for reasons I'm not sure of.

It does make me feel on the verge of a panic attack sometimes. My heart races, I might get really cold for no reason, and sometimes it makes me too nauseated to eat. There's also a lot of derealization but that's not unique to panic attacks for me. Also I get a lot of back and neck pains from the tension, and lately it's caused me to start clenching my jaw down really tight all the time without noticing it. I'm afraid I'm going to wear down my teeth if that doesn't stop.

Often when it's at its worst, the anxiety is mixed in with severe irritability so I just feel like going into a rage and destroying everything around me. Sometimes the anxiety and the irritability can become hard to distinguish from each other. Trying to keep all that down with no way to release it is hell on earth.