It depends on the job really. For awhile after I was first diagnosed, I couldn't work at all. Then I worked as a probate clerk which despite giving me much needed structure was awful. I was surrounded by death everyday, and the bureaucratic ******** just increased my rage. Eventually, after a series of other jobs, I found my way into academia. As long as I find meaning and intellectual engagement in my work and can maintain a routine, I do ok. That's not to say there aren't rough periods, but work usually helps me cope, lets me disappear into it. I do not discuss my illness with my colleagues. I don't want it to define me, and academia is a weird place full of weird people that isn't always as accepting as you'd hope.