i would say be very cautious. I had early onset menopause and had the Mirena IUD placed to try to balance my cycles. That's just a tiny bit of hormones and it made things really bad for me. I'm often very sensitive to meds but that was horrible. I was suicidal and IP twice in a few months because of it. When nothing controlled my BP symptoms we decided to pull the IUD and I immediately got better. Because of this my pdoc and gyn started watching for other cases of bipolar women reacting poorly to the Mirena and found several almost immediately.

I'm not saying hormone replacement is the same or that you'll have the same issues I had. Just be aware of what is going on as you go on the hormones and keep your pdoc and gyn both up to date on how you are feeling and if you feel it is affecting your moods.