Yes, I would distance myself.

How many chances can you give someone. You mentioned it to them before, they change then go back to blanking you.

There is no need to feel guilty. A friend would not ignore you while speaking to other people on social media (or wherever). Even if they were struggling, a true friend would tell you 'hey, i need to take some time out for self-care' but not just ghost you and be so inconsistent and hot and cold with you.

I don't see that as the mark of a true friend.