A PRN antipsychotic is extraordinarily helpful for me. Mine does happen to be Seroquel, but as others said, there are other possibilities. Like others, Haldol has been used for me for extreme mania control, in the past. I also had a hospital psychiatrist say that Zyprexa should always be on the table as an "emergency" medication. [It works great for my bipolar disorder, but is very unfriendly for me in terms of side effects, so a no-go as a "regular" med.]