Currently the best med I've found to treat my depression is Seroquel. It gets me from severe to moderate depression, at least some days, so it's better than nothing, but I still can't function well at all (although I do keep trying, I'm not sitting around doing nothing). And there's no gradual improvement over time, the depression stays constant, just at a slightly higher level than without the Seroquel. And as soon as I try to taper the Seroquel, the depression worsens so hard and fast, I'm back where I started within two days. Is this what's considered a "successful" treatment? I would like to transition to a maintenance treatment at some point that has fewer side effects, like lamotrigine, but right now that just doesn't cut it without the Seroquel. I don't want to be on Seroquel forever. Surely this can't be as good as it gets? I'm still trying to get ECT treatment, but I just want to consider my options here in case that doesn't work out.