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I started out on a low dose, 75mg. regular. I noticed more energy and clarity within a week. That I wasn't falling asleep all day was uplifting in itself.
Gradually increased to 100mg., after about a month 200mg. 200mg. is the lowest clinical dose. The side effects I noticed were occasional nausea that wasn't terrible and didn't last long. After several days on 200mg I had an almost complete loss of appetite.
Tomorrow I'm starting on 150mg. XL. Apparently it's standard to begin on the regular Wellbutrin before moving on to XL.
So I'll say that I felt an uplifting about a week in. But- it's important to know that I also take the AD Pristiq (50mg.).
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