Trilafon (perphenazine) is an old one. None of the newer AP's (I tried all of them) ever helped my anxiety one bit. Plus, they have so many deleterious side effects. Finally, my pdoc prescribed Trilafon (at a low dose) and finally, after 9 years of battling hellish anxiety it calmed down. Therapy definitely helped, too - but I couldn't have calmed the anxiety without the med. The only bad side effect I've had from the Trilafon is it causes tremor. But then, most psych meds do. I take it at night because it causes very mild sleepiness. There's another member of this board, haven't seen him for awhile, but he also takes Trilafon for anxiety & says nothing else has helped him.
It's my wish that pdocs would go back to using the older AP's, in lower doses, more frequently. The new ones cause so many health issues and aren't always helpful.