You can adjust your medication(s) and still mourn the loss of your friendships. My best friend of 53 years died in February very suddenly of heart failure. I've been grieving her death since she died; it turned my world upside-down. I also added in (at my pdoc's suggestion) another AD. Due to the grief, I was falling into a major depression. Now I don't have to give all my energy to the depression - but I can grieve and process properly.