Sorry to hear Fuzzy bear, I also have bad luck with medication too I tired the likes of at least 20 antidepressants lots of them either didn't work or gave me mood swings. I'm on Pristiq now but that's not perfect either. It has helped massively with my antidepressant but gives me constipation and low libido. I hope they give you alternative treatment because not everyone can tolerate synthetic drugs. Have you tried St John warts I heard it's good for depression