Like others have said, each med I take targets a different symptom and I don't think any of them are more important than the other - the constellation of meds is what works: lithium for mania, lamictal for depression, zoloft for anxiety, seroquel for sleep, and adderall as needed to focus. I started with lithium, and each one thereafter was added when the previous med stabilized it's target symptom. The stabilization of one symptom revealed the next that needed to be addressed.