@Brokenheartedmom, I struggled to find the post of yours that BethRags quoted (computer issues), but wanted to also welcome you here.

Obviously we don't know the issues regarding some of your daughter's family members distancing from her. However, it is important that they try to learn at least a little bit about bipolar disorder. Have you considered buying a good book on the disorder and after reading it (if you haven't already), shoving it in your son's hands? Perhaps he wouldn't read the whole thing, but even skimming might be helpful. If your daughter actually did something that hurt him (and others) because of bipolar behavior, time may help a bit with forgiveness and understanding. If there is a deep stigma present, that (and some other prejudices) do ease in people with time. Again, education is key. Sometimes a person must have their own hardships to commiserate with others'. In any case, I feel for your daughter and you. Struggling/suffering from a mental illness is hard enough. Being rejected by others is the icing on the cake of pain. My family members didn't exact distance from me, but they weren't sufficiently supportive, either. But I did have friends and colleagues distance from me. It's a hard pill to swallow.