My reaction to my interaction with others certainly causes depression, or makes my existing depression worse. I don't think people are setting out to make me feel like shite, but how I feel about myself in response to a situation can send me into a downward spiral. Obviously if people are deliberately trying to make me feel awful then it's best to cut them loose and that causes depression/grief, because I've lost someone else in my life.

I have a strong basic need for belonging to a family or family like group and an need for intimacy - and those are missing from life for reasons that are beyond my control and that certainly is a cause of my depression.