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Originally Posted by sarahsweets
Moderna and Pfizer are nearly equal in effectiveness.
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You're actually correct, Sarah! I keep track of
Katelyn Jetelina emails regarding updates from Your Local Epidemiologist, and it looks like mixing Pfizer booster with original Moderna series is nearly the same effectiveness as getting the Moderna booster with the original Moderna series (though I forgot if the research only showed the full Moderna jab and not the 1/2 shot).
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"After the primary Moderna series, there was benefit from either a Moderna or Pfizer booster. There was really no difference between the two."
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That's only if you've had the original Moderna series for jabs #1 and #2.
If you've had the J&J, the research suggests the following:
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"The most benefit, by far, was for those with a primary J&J shot. A Moderna booster gave the greatest benefit to J&J folks (56.1 fold increase in IgG; 76.1 fold increase in neutralizing antibodies). Pfizer also worked very well (32.8 fold increase in IgG; 35 fold increase in neutralizing antibodies). There was minimal increase with a J&J booster (4-fold increase)."
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And if you've had the Pfizer, the research suggests the following:
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"After the primary Pfizer series, the greatest benefit was from a Moderna booster. But a Pfizer booster helped a lot too."
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It looks like the Moderna booster works best for those who had the J&J initial jab or the Pfizer jabs #1 and #2.
It looks like the Pfizer or Moderna booster would work best for those who had the Moderna jabs #1 and #2.
Again, I don't know if they used the full Moderna dosage in their study or the 1/2 dosage that is now being doled out.