I sometimes take chamomile with CALM (magnesium) drink. Other times I just take 81 mg chewable aspirin with extra strength coated Tylenol. Other times I'll take melatonin 6 mg with chamomile tea and a Tylenol. I've not yet tried my Tylenol PM (alone, no other supplements), but I plan to try that today. I'm in pain as we speak, and I forgot if I ever slept at all.