There are times when I feel I'm on way too many meds, but I've been remarkably stable for quite some time on my cocktail. I take 6mg Vraylar, 20mg Trintellix, & 500mg Depakote ER twice a day. I might be killing my liver, but I can't argue with the mental health results. There are also times when I wonder if it's really the meds, or if I'm just experiencing the "natural order" of things. It's so hard to tell.