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therealstacy:
I'm sorry you're in this situation. The posters above have given a lot of good input. Since you've been friends with this woman for so long, ten years, a long time, i think it is worth having a conversation to try and work it out. I let a friend go last Summer because she was insensitive but i'd only met with her twice and i felt if i had to instruct her on how to be nice to me it wasn't worthwhile. But that was a brand new friend. You've put ten years into this person so it's worth trying to see if you can adjust things so you're more comfortable.
I know what you mean about desperation. I've had a lot of bad romance out of desperation. Trying to get more comfortable being alone, but it isn't easy.
Best of luck!