Thread: Roll Call 193
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Old Jun 11, 2022, 03:24 PM
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Desoxyn Desoxyn is offline
Metaphysic
 
Member Since: Aug 2016
Location: The Netherlands
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Originally Posted by Desoxyn View Post
I don't know much about Caplyta but it's supposed to be a negative symptom antipsychotic - I wanted to try it for a while but was just waiting until it was available and forgot about it.
It's similar to Haldol except good for depression - Could have less side effects idk.

Edit: "Lumateperone is a serotonin, dopamine, and glutamate MODULATOR with the potential to treat schizophrenia with few adverse effects"

"Specifically, lumateperone acts as a potent serotonin 5-HT2A receptor antagonist, a dopamine D2 receptor presynaptic partial agonist and postsynaptic antagonist,10 a D1 receptor–dependent modulator of glutamate, and a serotonin reuptake inhibitor."

So it's similar to clozapine but chemical structure like haldol

It blocks 5HT2A receptors as much as clozapine but less D2 receptors than clozapine.

Last edited by Desoxyn; Jun 11, 2022 at 03:45 PM.
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