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Originally Posted by Desoxyn
I don't know much about Caplyta but it's supposed to be a negative symptom antipsychotic - I wanted to try it for a while but was just waiting until it was available and forgot about it.
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It's similar to Haldol except good for depression - Could have less side effects idk.
Edit: "Lumateperone is a serotonin, dopamine, and glutamate MODULATOR with the potential to treat schizophrenia with few adverse effects"
"Specifically, lumateperone acts as a potent serotonin 5-HT2A receptor antagonist, a dopamine D2 receptor presynaptic partial agonist and postsynaptic antagonist,10 a D1 receptor–dependent modulator of glutamate, and a serotonin reuptake inhibitor."
So it's similar to clozapine but chemical structure like haldol
It blocks 5HT2A receptors as much as clozapine but less D2 receptors than clozapine.