Not as monotherapy (I took it also with Depakote ER) and only in pill form. I give it huge credit (with Depakote) for squashing what was a years long struggle with severe mania and mixed mania, with psychosis. However, with Depakote I was left depressed, but that was likely more a mood crash than necessarily the medication's fault.

I had rapid weight gain and poor blood test results, but again I think Depakote was more to blame. What I did 100% attribute to Invega was hyperprolactinemia. It is a risk, but especially if you're vulnerable. I had also had hyperprolactinemia from Risperdal, which is a related antipsychotic. Not everyone has this issue and some that do can be treated for it or even live with it. The residual permanent effects for me were an increase in breast size, which for women (like me) isn't necessarily a negative. It is more so for affected men.